How stressed cells put the brakes on protein 'shipping'

Cells synthesize proteins in the endoplasmic reticulum (ER), and these proteins are transported to the Golgi apparatus for distribution to their ultimate destinations inside and outside the cell. The structures that transport proteins from the ER to the Golgi apparatus are called COPII vesicles; the processes that regulate the formation of COPII vesicles are only partially understood.

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