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Triple-negative breast cancers, which are more frequently diagnosed in younger women, are a subtype of breast tumor characterized by the absence of hormone receptors and HER2 overexpression. As a result, they do not respond to hormone therapy or HER2-targeted treatments. Their prognosis is generally less favorable than that of other breast cancer subtypes.
With around 75,000 new cases per year, breast cancer is by far the most common cancer among women in Germany. Using digital breast tomosynthesis in the breast cancer screening program could prevent around a quarter of invasive interval cancers that occur within two years after a digital mammogram.
Patients have been left feeling suicidal after feeling like their doctor was saying their symptoms were 'all in their head'—according to research from the University of East Anglia and the University of Cambridge.
One of the more impressive data sets at this year’s ESMO came from a Roche study of its drug divarasib, which treats lung cancer.
Feeling overwhelmed by the noise and chaos of parenting? You're not alone.
Weightlifting has a reputation for "bulking up," so it may not be the first type of exercise you choose when you want to lose weight.
Research led by internist-nephrologist Dr. Michele Eisenga shows that SGLT2 inhibitors, a class of drugs widely used to treat type 2 diabetes, heart failure and chronic kidney disease, consistently increase hemoglobin and hematocrit levels.
The deal would make the Catholic system one of the largest operators of outpatient surgery centers.
The American Heart Association, American Academy of Pediatrics, American College of Obstetricians and Gynecologists and the Society for Maternal-Fetal Medicine have released a publication that redefines heart health in girls and women. The organizations together outline four distinct "Female Life Stages" offering women and health care professionals a chance to have heart health conversations from puberty through menopause and beyond.
Adding a personalized mRNA-based cancer vaccine to immunotherapy after surgery for high-risk melanoma reduced the risk of recurrence or death by 42%, according to results from the phase 3 INTerpath-001 trial presented at the ESMO Congress 2026. The vaccine, intismeran autogene, was given alongside pembrolizumab and compared with pembrolizumab alone.
The Trump administration removed several security, privacy and transparency requirements for vendors of EHR software.
Reading a sentence, following a conversation, solving a problem or deciding what to do next: all of these rely on working memory. It allows the brain to hold information in mind for a few seconds, even after the stimulus has disappeared, to be able to compare it with new information, manipulate it and use it to guide our behavior. It therefore plays an essential role in the transition from perception to thought, and from thought to action.
An international phase 3 clinical trial that treated patients with high-risk localized and locally advanced prostate cancer with apalutamide—a next-generation neoadjuvant androgen-receptor pathway inhibitor (ARPI)—plus hormone therapy before and after prostate cancer surgery was further validated by a substudy demonstrating a reduced risk of metastasis or death compared with standard of care.
An extra hour of sleep is on the way for most Americans, though the "fall back" to standard time will bring darker afternoons, too.
"Please go brush your teeth, get dressed and brush your hair." These are familiar morning requests that parents make to preschool and school-age children.
Long COVID is often associated with symptoms such as persistent fatigue, shortness of breath and brain fog. But evidence increasingly shows that long COVID may have a broad effect on the cardiovascular system, as well.
A rare, aggressive cancer, commonly found in the uterus, limbs and abdomen, behaves differently depending on where it is found in the body, according to new research.
Tadalafil is a prescription drug closely related to Viagra. It is used to treat erectile dysfunction (ED) and the urinary symptoms of an enlarged prostate. Both competitive and recreational athletes sometimes use it too, to treat pulmonary arterial hypertension (PAH), a condition that can limit how well the body tolerates exercise.
When the clocks go back in October, millions of Britons welcome an extra hour in bed. But by the evening, with darkness arriving before many people finish work, that small luxury may seem a distant memory.
A new study using wearable brain imaging has shown what happens in the human brain when someone learns to play a musical instrument. The results revealed the patterns of brain activity that enable us to play an instrument, in this case a violin, and how having just a single lesson significantly changes those patterns of activity.
Much of what we know about the world comes from experiences we have never had ourselves. A child observes how a parent reacts to a situation, which influences their own future actions. Someone becomes more cautious after seeing another person in danger.
Adding darolutamide to standard treatment for aggressive prostate cancer reduced the risk of the disease spreading in an international phase 3 trial.
A Northwestern Medicine study has identified a previously unrecognized population of immune cells that appears to fuel harmful blood vessel growth in multiple blinding eye diseases, according to the study published in the Journal of Clinical Investigation. The discovery could open the door to new treatments for patients who don't respond to existing therapies, said the study's senior author Jeremy Lavine, M.D., Ph.D., assistant professor of ophthalmology.
For patients with autoimmune disease, higher baseline B-cell counts and systemic inflammation are associated with development of cytokine release syndrome (CRS) after chimeric antigen receptor (CAR) T-cell therapy, according to a study published in the November issue of The Lancet Rheumatology.
In patients with extensive-stage small cell lung cancer (ES-SCLC), tarlatamab, a bispecific T-cell engager, plus durvalumab as first-line maintenance therapy extended median overall survival by more than eight months, more than tripled progression-free survival and reduced the risk of death by 58% compared to durvalumab alone, according to results of the phase 3 open-label, multicenter, randomized DeLLphi-305 study.
Dengue cases in Florida keep climbing about a month after three counties declared states of emergency over the mosquito-borne illness.
Conversational AI chatbots are a relatively new technology, but they are now ubiquitous, embedded in everything from customer service platforms to personal productivity tools. Such is their rapid adoption that potential negative consequences are yet to be fully understood.
As many as one in six adults face fertility difficulties worldwide, research has shown, and the challenge becomes harder as they age. Starting around age 35, the risk of eggs carrying an abnormal number of chromosomes rises steeply, contributing to declining fertility and increasing miscarriage rates. Understanding why these errors occur is essential for improving reproductive outcomes.
On a busy street in Karachi, Pakistan, a health care worker kneels down so she's eye to eye with a toddler. She squeezes two drops of liquid onto the child's tongue. Then she takes out a purple marker and colors the child's pinkie fingernail so everyone can see that this toddler is now vaccinated against polio.
The biggest international study ever on risky play has found that children who have more opportunities for outdoor adventurous play tend to have better physical and mental health, as well as improved social and cognitive development.