Alpha-1 antitrypsin deficiency may raise preterm birth risk, genetic analysis suggests

Researchers at the University of Oulu have identified alpha-1 antitrypsin as a potential target for preventing spontaneous preterm birth. In a large genetic study of more than 200,000 mothers, a variant in the SERPINA1 gene, which encodes alpha-1 antitrypsin, was associated with shorter pregnancies.

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