Letter from the Editor-in-Chief: The Good and the Hard of Life on GLP-1s

GLP-1 medications such as semaglutide and tirzepatide have changed daily life for millions of people, though side effects are common. Photo by Getty GLP-1 medications like semaglutide and tirzepatide can lead to significant weight loss and may help reduce inflammation, improve mobility, and quiet persistent thoughts about food. Many people report life changing results after years of unsuccessful diets. A Healthline story on Mayim Bialik’s GLP-1 side effects became our most engaged Facebook post of the year, as thousands of commenters shared hard side effects and life changing results. Research also increasingly links GLP-1s to benefits beyond weight loss. Healthline’s Editor-in-Chief Robin Hough talks with his mom, Catherine, who lost 56 pounds on tirzepatide, and a registered nurse who has lost over 50 pounds, about the benefits, side effects, and cost of long-term treatment. “Years of diets that worked for a couple of months, then gave all the weight back and more. Now the food noise has gone quiet,” a GLP-1 user shared. In June, our brilliant News team published a piece about actor Mayim Bialik and her challenging experience with GLP-1 side effects. It did well, like many of th…

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