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phys.org · Sep 30

Unlocking the cell's supply chain: How cholesterol keeps cellular recycling centers running

Mention cholesterol, and most people will think of clogged arteries or health warnings. But inside the microscopic universe of the human cell, cholesterol has a drastically different job description as an indispensable cellular lifesaver. A study led by the Lee Kong Chian School of Medicine (LKCMedicine) at Nanyang Technological University, Singapore (NTU Singapore), shows how cells rapidly dispatch cholesterol to reinforce their "recycling centers" called lysosomes, preventing them from bursting while breaking down worn-out cellular machinery.

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