How the treatment of interleukin-6-driven diseases can be refined

Interleukin-6 (IL-6) is a contradictory molecule in immunology. It helps the liver regenerate after injury and protects against infections, yet it also drives chronic inflammation in rheumatic diseases, inflammatory bowel disease and atherosclerosis. Current drugs block IL-6 across the board: They protect against inflammation but also switch off its beneficial functions.

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